DefenAge is one of very few skincare lines we carry in our offices and recommend. We are blown away by this new technology and our patients are loving the results!
These products are safe for all skin types and tones, and can be used alongside other skincare products.
Defenage Quick Facts
- Patented new skincare technology
- Turns on your body’s own anti-aging powers
- Clean beauty products
- Available for purchase in both of our nj offices
DefenAge: Skincare We Stand Behind
If you’re looking for a new skincare routine with a few, potent steps, DefenAge offers the very best technology available today to refinish and rejuvenate the skin. Most patients start with this line with 1 of 3 paths:
- Start with a treatment for your biggest problem area: eyes or neck
- Start with the clinical power trio to see the impact on overall facial skin anti-aging
- Replace your serum and see results that convince you to try more
6 Week Perfection Neck Cream
We are typically not big believers in neck creams: they often overpromise and deliver next to nothing in terms of results. But this cream has unique technology in it that does seem to make a big difference in neck skin texture, quickly.
Our patients report that the crepey skin in their neck is much-improved when they use this neck cream consistently. It’s still not at the level of result you can get with surgery or a series of skin tightening treatments, but it is a noticeable difference, and it’s significantly less expensive and not at all invasive. As always, prevention and maintenance as frequently as possible beginning as early as possible will get you the best results.
Key Ingredients & Active Technologies
- Age-Repair Defensins® | 1X | DefenAge’s Exclusive – tells your skin to create new cells, for a more youthful neck (retinol alternative)
- Niacinamide – restores the skin’s moisture barrier, brightens, hydrates, firms
- Fine Blends of Natural Antioxidants (including Vitamin E), Enzymes, and Hydrating Technologies – antioxidants fight oxidative stress which can age the skin
Suitable for all skin types.
- When to Use: A.M. and P.M., as first step after cleansing
- Results: start to appear at 1 week, finalized after week 6
- How to Use: After cleansing (and any exfoliation), place 1 pump of the neck-tightening cream onto fingertips twice daily. While skin is still moist, lightly massage the firming neck cream onto the skin with short lifting motions using the fingers of your right hand to apply to the left side of the neck and décolleté, and vice versa. Start above the breast line and work up to the jawline and back of the neck. Wait 30 seconds, then apply 8-in-1 BioSerum.
- Best For: crepey skin texture, fine lines, firming
- Availability: in-office purchasing only, at both locations
- Cost: $108.00 for 1.5 oz Mega Jar Size
3D Eye Radiance Cream
This award-winning eye cream has been dermatologist and ophthalmologist-tested and is non-irritating and safe for use by contact lens wearers.
Key Benefits:
- Visibly lifts, firms, and smooths the upper eyelids.
- Fades dark circles and diminishes the appearance of skin discoloration.
- Reduces puffiness and “bumps” under the eyes.
- Fades the appearance of crow’s feet and fine lines around the eyes.
- Safe to apply to both the upper lid and under the eyes.
- Can be used together with a retinol product if retinol is tolerated; effective as a retinol alternative brightening eye cream for retinol-sensitive skin.
- Perfect as a standalone eye product; also recommended by dermatologists as a complement to aesthetic treatments, including skin resurfacing, microneedling, fractional lasers, and for post neuromodulator and filler injections around the eyes and upper face.
- Free from irritants, suitable for all skin types, and safe for contact lens wearers.
- Metal applicator with Cooling Tip Technology allows a clean, gentle, finger-free application, providing soothing benefits.
Key Ingredients & Active Technologies
- Age-Repair Defensins® | 1X | DefenAge’s Exclusive – tells your skin to create new cells, for a more youthful undereye (retinol alternative)
- Hyaluronic Acid – visibly plumps and smooths the skin with hydration
- Fine Blends of Natural Antioxidants (including Vitamin E), Enzymes, and Hydrating Technologies – antioxidants fight oxidative stress that can age the skin
Suitable for all skin types.
- When to Use: A.M. and P.M., as first step after cleansing
- Results: start to appear at 1 week, finalized after week 6
- How to Use: After cleansing, while skin is still moist from rinsing, pump a drop of cream onto applicator. Lightly dab three dots of cream above and below each eye. Using applicator, massage cream around eyes.
- Best For: crepey skin texture, fine lines, firming
- Availability: in-office purchasing only, at both locations
- Cost: $108.00 for 0.5 oz.
Clinical Power Trio: Includes Full Size 24/7 Barrier Balance Cream, 8-in-1 BioSerum, & 2 Minute Reveal Masque
A clinical study showed that this trio of products offered all of the benefits of retinol, without the irritation or sun sensitivity1.
Key Ingredients & Active Technologies
- Age-Repair Defensins® | DefenAge’s Exclusive – tells your skin to create new cells, for a more youthful undereye (retinol alternative)
- Niacinamide – restores the skin’s moisture barrier, brightens, hydrates, firms
- Hyaluronic Acid in Two Forms: Liposome Encapsulated (Cream) & Low Molecular Weight (Serum) – visibly plumps and smooths the skin with hydration
- Fine Blends of Natural Antioxidants (including Vitamin E), Enzymes, and Hydrating Technologies – antioxidants fight oxidative stress that can age the skin
How to Incorporate Into Your Routine:
The Clinical Power Trio includes 3 full-size products, which should be used in order:
2-Minute Reveal Masque, Net Wt. 2.5 oz.
Once or twice a week after cleansing, as part of your P.M. routine, dry skin thoroughly. Apply a dollop of masque about the size of a quarter to the face and jawline. Using dry fingertips, gently massage the masque in a circular motion for 20 seconds or less, depending on skin sensitivity. Avoid the eye area. Wait 2 minutes. With moistened fingertips, massage until the crystals are completely dissolved. Rinse face thoroughly. Follow with step two, the 24/7 Barrier Balance Cream.
This step is not recommended for acne, extremely sensitive or ablated skin. Our doctors will be happy to recommend a different routine that includes proper exfoliation for your skin.
24/7 Barrier Balance Cream, 1.5 fl. oz.
Use this moisturizer twice daily after cleansing, both morning and night. Place up to 2 pumps of cream onto fingertips, then — while skin is still moist — lightly massage with fingertips over the entire face. Avoid the eye area. Wait 30 seconds; then apply step three, the 8-in-1 BioSerum. Suitable for all skin types.
8-in-1 BioSerum, 1 fl. oz.
Apply 30 seconds after applying the Barrier Balance Cream, both morning and night. Place 1 pump of serum onto fingertips. While skin is still moist, lightly massage with fingertips, first around the eyes, then over the entire face. Use a second pump on the neck and décolleté. Follow with sunscreen (we prefer EltaMD). Suitable for all skin types.
- When to Use: A.M. and P.M., see use details above
- Results: start to appear at 1 week, finalized after week 6
- How to Use: See details above for how to incorporate all 3 steps into your routine, to be used twice daily.
- Best For: enlarged pores, texture & fine lines, pigmentation changes, sun damage; takes the place of 8 different serums.
- Availability: in-office purchasing only, at both locations
- Cost: $365.00 for all 3 full size products
8-in-1 BioSerum
DefenAge’s iconic bestseller with patented Defensins technology, this serum will make a noticeable change in your skin by turning on your skin’s stem cells for dramatic cell renewal and turnover. This serum combines the benefits of up to 8 different serums.
Key Benefits:
- Rejuvenates smoothness.
- Improves overall visible skin health and quality.
- Minimizes the look of fine lines, wrinkles, pores, skin pigmentation, and discolorations.
- Promotes radiance and revives the skin’s natural moisture for an ultimate glow.
- Brightens the overall skin tone and clarity and enhances skin luminosity.
- Renews the feeling of skin firmness, elasticity, and texture.
- Helps improve the appearance of skin redness.
- Promotes the skin barrier and skin immunity.
Key Ingredients & Active Technologies
- Age-Repair Defensins® | 5X | DefenAge’s Exclusive – tells your skin to create new cells, for a more youthful neck (retinol alternative)
- Niacinamide – restores the skin’s moisture barrier, brightens, hydrates, firms
- Fine Blends of Natural Antioxidants (including Vitamin E), Enzymes, and Hydrating Technologies – antioxidants fight oxidative stress which can age the skin
- Hyaluronic Acid | Low Molecular Weight – a hyaluronic acid that’s able to deeply penetrate the skin for true, lasting moisturization
Suitable for all skin types.
- When to Use: A.M. and P.M., as last step in routine, after cream or moisturizer
- Results: start to appear at 1 week, finalized after week 6
- How to Use: Place 1 pump of 8-in-1 BioSerum onto fingertips. Lightly massage with fingertips first around eyes, then over entire face. Use a second pump on neck and décolleté. Follow with sunscreen.
- Best For: more youthful-looking skin: pore size, texture, redness, fine lines, moisture, elasticity, light discolorations on face and neck
- Availability: in-office purchasing only, at both locations
- Cost: $228.00 for 1.5 oz Mega Size
24/7 Barrier Balance Anti-Aging Cream
Layered on directly after cleansing and before the serum, this cream contains a unique blend of Defenage’s premiere technology, Defensins, which repair the damage of aging by turning on our body’s natural cell-replacement system.
Key Benefits:
- Innovative formula helps replenish and balance the skin’s natural barrier.
- Revives radiance and improves overall tone and texture for remarkably smooth, even skin.
- With regular use, skin looks brighter and feels firmer.
Key Ingredients & Active Technologies
- Age-Repair Defensins® | 1X | DefenAge’s Exclusive – tells your skin to create new cells, for a more youthful face & neck (retinol alternative)
- Niacinamide – restores the skin’s moisture barrier, brightens, hydrates, firms
- Nine Blends of Natural Antioxidants, Enzymes
and Hydrating Technologies – antioxidants fight oxidative stress that can age the skin; this blend also soothes the skin and increases hydration - Hyaluronic Acid | Liposome – Encapsulated – a unique hyaluronic acid formulation that hydrates and smooths out texture
Suitable for all skin types.
- When to Use: A.M. and P.M. as first step after cleanser
- Results: start to appear at 1 week, finalized after week 6
- How to Use:
Twice daily after cleansing, place up to 2 pumps of cream onto fingertips. While skin is still moist, lightly massage with fingertips over entire face. Avoid eye area.
- Best For: skin with compromised barrier, aging skin that’s lost its luminosity, aging skin wishing to see maximum results from skincare (when paired with BioSerum)
- Availability: in-office purchasing only, at both locations
- Cost: $108.00 for 1.5 oz Full Size
10 Luxe Hand & Body Cream
Finally, a medical grade skincare cream for the hands and entire body that’s proven to make a visible difference in aging. The 10 Luxe Cream for Hands & Body contains all of the anti-aging benefits of Defensins that Defenage’s line for the face offers, along with squalene and niacinamide, for deep hydration and firming.
Key Benefits:
- Visibly enhances firmness and cosmetic elasticity.
- Improves the appearance of crepey skin.
- Refines the surface skin texture.
- Provides both instant and long-lasting hydration including in dry climates. Boosts natural moisture retention. Skin feels firmer and plumper immediately.
- Relieves the feeling of dryness and itching.
- Balances the skin’s barrier function.
- Promotes the skin’s natural hyaluronic acid, laminin, and elastin.
- Improves visible skin thickness.
- Reverses signs of skin aging, premature aging, and sun damage.
- Effective on elbows and knees; visibly revives their smooth texture and revitalizes softness.
Key Ingredients & Active Technologies
- Age-Repair Defensins® | 5X | DefenAge’s Exclusive – tells your skin to create new cells, for more youthful skin (retinol alternative)
- Niacinamide – restores the skin’s moisture barrier, brightens, hydrates, firms
- Fine Blends of Natural Antioxidants (including Vitamin E), Enzymes, and Hydrating Technologies – antioxidants fight oxidative stress that can age the skin
- Hyaluronic Acid | Low Molecular Weight – a hyaluronic acid that’s able to deeply penetrate the skin for true, lasting moisturization
Suitable for all skin types.
- When to Use: A.M. and/or P.M., after shower/bath
- Results: start to appear at 1 week, finalized after week 6
- How to Use: Apply this lotion for aging skin once or twice daily after showering or bathing. Smooth and lightly massage the hand and body cream from ankles to waist, then hands, arms, and shoulders, followed by the rest of the body. Apply the 8-in-1 BioSerum on elbows, knees, and other challenging areas to maximize results.
- Best For: dry, itchy skin (reduced barrier function) or skin with reduced hydration due to sun damage (chronically crepey, thin, with lots of fine lines, and a rough texture)
- Availability: in-office purchasing only, at both locations
- Cost: $138.00 for 4.0 oz Full Size
1-Step Multiple Cleanse
This hydrating cleanser is powered with prebiotics, for healthy, stronger skin and the perfect boost for sensitive and irritated skin (think acne, rosacea, red & stinging skin). The Defenage system relies on cleansing twice a day, to create a clean surface for delivering their defensins technologies. but twice-a-day cleansing can be stripping and damaging to sensitive skin, which is why they formulated this special hydrating single-step cleanser to prep skin.
Key Ingredients & Active Technologies
- Natural Prebiotics – strengthens skin’s natural biome and reduces bad bacteria
- No-Soap Technology – cleanses without disrupting skin barrier, to allow skin to heal over time, even with twice-a-day use.
Suitable for all skin types.
- When to Use: A.M. and P.M., as first step (but after an eye makeup remover)
- Results: start to appear at 1 week, finalized after week 6
- How to Use: Place a dime-sized portion of the hydrating facial cleanser gel onto fingertips. Gently massage the facial wash over dry skin for 15 seconds. Moisten fingertips and massage using circular motions. Repeat until a white face wash cleansing milk develops. Rinse the gentle face wash off well with warm water. If desired, use a clean cloth or cleansing sponge to remove the excess face cleanser. Pat dry with a clean towel.
- Best For: skin of all types, including sensitive skin. Will remove heavy makeup (but not for use on eyes)
- Availability: in-office purchasing only, at both locations
- Cost: $53.00 for 5.0 oz Mega Size
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Read MoreSources:
1. Taub A, Bucay V, Keller G, Williams J, Mehregan D. Multi-Center, Double-Blind, Vehicle-Controlled Clinical Trial of an Alpha and Beta Defensin-Containing Anti-Aging Skin Care Regimen With Clinical, Histopathologic, Immunohistochemical, Photographic, and Ultrasound Evaluation. Jounal of Drugs in Dermatology. 2018 Apr 1;17(4):426-441. PMID: 29601620.Recap of Study Findings
2. Ebook Explaining Defensins Technology, from Defenage Corporate
Dr. Renata Wix-Harris has extensive experience as a general surgeon and work in the plastic surgery department has helped to her to become an excellent laser liposuction surgeon. She is also skilled at laser and energy-based skin therapies, injectables, and non-invasive body contouring.